Jayesh Bellare Research Group

Hollow fiber membrane (HFM) technology is one of the main research areas of our group. Our group has built an in-house pilot plant for spinning HFMs using a dry-wet spinning technique. With it, we are preparing new types of HFMs for three main areas: biomedical engineering, water treatment, and gas separation applications. Our research on the HFMs has resulted in several papers and patents.

Tissue engineering and regenerative medicine is a multi-disciplinary and inter-disciplinary approach to develop engineered substitutes in the form of grafts or scaffolds to maintain, restore, and improve the functioning of tissues. The gold standard is to use auto-grafts, allografts, xenografts, but because of their supply shortage and other disadvantages like extended morbidity, two surgical sites, disease, and infection transfer make the research and development of alternatives an urgent need. Our research work in this field is mainly focused on the development…

Nanomedicine is the discipline of medicine in which nanoscale materials is used for the diagnosis, monitoring, control, prevention, and treatment of disease. Nanomedicine holds tremendous promise to transform medicine across disciplines and specialties, but this promise has yet to be fully understood. Our lab works in a wide field of nanomedicine, including allopathy, as well as alternative medicine. Our main objectives are to find out the mechanism of drug actions and their efficacy in various in-vitro and in-vivo models.

The human heart has four chambers which are separated into two superior atria and two inferior ventricles. The wall tissue of the human heart called septum which separates the chamber of the heart, one of the septa gets defected is known as a septal defect. It is classified into two types based on the location, if it is in the upper chamber of the heart known as Atrial Septum Defect (ASD) whereas in the lower chamber is known as Ventricular Septum Defect (VSD). ASD/VSD is nothing but a hole or opening between upper/lower chambers of the heart to allow blood to…

Drug delivery using biomaterial-based carriers is one of the eminent themes of our group. We aim to harness the biocompatibility of various polymers and elemental materials and, use these as carriers for therapeutic purposes. A plethora of materials and chemical modifications allow us to tailor our carriers in ways that suit a wide variety of biological applications. Our group, in particular, has been interested in developing small molecular systems for drug delivery into the eye. The eye is a self-sustained fortress inside the human body. Drug…