Siddhartha Das

Education:

Ph.D. (Bioengineering), Indian Institute of Technology Bombay, Mumbai, India

ORCID iD: http://orcid.org/0000-0001-9669-6732

Google site: https://sites.google.com/view/siddharthadasphd/home

Thesis research topic: Electrospun biodegradable nanofibres induced tissue engineering approaches in maxillo-mandibular region

Research Summary:

The contemporary use of implants has witness gradual evolution with significant advances coming from the specialty of dental implantology. The real expectation of endosseous implant was to accomplish their task through mechanical anchorage with bone i.e. osseointegration. Thus, the concept of osseointegration has been examined under various scenarios to understand the relationship of the material characteristics and its subsequent osseous healing response necessary for the proper stability of the metallo-biological interface. It is of great significance and the basis of the current treatment protocol regarding the least possible time required by patients to perform the complex chain of events that may lead to early osseointegration. Additionally, periodontal ligament, a specialized connective tissue attachment is absent in the events of osseointegration for dental implants. Hence, the work combined electrospun nanofibres technologies and implants so as to pursue applied bioengineering concepts yielding advance implant beyond the present state-of-the-art.

Keywords:

Bioengineering; proof of concept trials; preclinical trials; endosseous titanium implants; electrospun nanofibres; tissue engineering;  biomaterials; neural tissue engineering; mesenchymal stem cells

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