Cell-death process, which occurs ubiquitously under normal and healthy conditions, is disturbed in diseased tissues. Cell-death process can be viewed as an outcome of a network of reactions. How does the network dynamically orchestrate the overall cell-death outcome? Can the network be re-wired to reverse the disturbances in the cell-death process? The goal of this project is to understand the cell-death process by developing a kinetic model of the network of reactions and validating with experimental data.