Biochemical signaling network for periodic forcing within sperm flagella.


Sperm motility is critical to fertilization and reproduction in animals. There remain several gaps in the knowledge base about the signaling mechanisms that govern conversion of chemical energy to mechanical work leading to flagellar beating as well as sperm steering and homing. The goal of this study is to build biochemical networks from available literature and propose models that explain and predict sperm motility in response to chemo-attractive molecules. We intend to use of MATLAB® for this project.