Start
Jul 15, 2013 - 16:00
End
Jul 15, 2013 - 17:00
Venue
Creativity Hall (Room 118) Chemical Engineering
Event Type
Speaker
Prof. Abhyudai Singh Dept. of Elec. and Comp. Engg. Univ. of Delaware
Title
Stochastic Inference of Regulatory Networks Inside Living Cells
Abstract In the noisy cellular environment many mRNA and protein species occur at low integer molecular counts and hence are subject to large stochastic fluctuations in copy numbers over time. Far from being a hindrance signatures of protein/mRNA noise levels can be informative about the underlying gene network topology. In this talk I will present recently developed mathematical techniques that harness fluctuations in the levels of biochemical species for systems identification of gene regulatory networks. Finally I describe our current efforts in using these techniques for reverse engineering the genetic circuitry of the human immunodeficiency virus (HIV). About the speaker Abhyudai Singh is an Assistant Professor in Dept. of Elec. and Comp. Engg. Univ. of Delaware. His research interests are in the area of Systems and Control with applications to systems biology and medicine.