Start
Nov 19, 2015 - 17:00
End
Nov 19, 2015 - 18:00
Venue
Room # 118 Chem. Engg. Dept.
Event Type
Speaker
Dr. Ramesh Raliya Research Scientist Nano Research Facility Aerosol and Air Quality Research Laboratory (AAQRL) Department of Energy Environmental and Chemical Engineering Washington University in St. Louis St. Louis MO-63130 USA
Title
Nanotechnology-enabled bio-system engineering: applications and implications
Abstract: Unique characteristics of the nanoscale object drawn the attention of research community to create novel properties and look for possibilities to solve world’s arising problems ranging from hunger to medicine.In the present research work nanomaterials ranging from metal and metal oxide to advanced graphene nanostructure were synthesized with independent control over shape size composition surface properties and crystal phase using aerosol sol-gel and biosynthesis approaches. Applications including system biology of nanomedicine drug delivery nano-nutrient and nanosensor for sustainable livelihoodwere explored.In nanomedicine we developed morphologically controlled 100 nm vaterite nanoparticles as a pH neutralizer for cancer therapy. The novel concept of extracellular pH environment modulator controls the tumor growth. An attempt was made to develop an aerosol-baseddrug delivery to the brain by axonal transport. Findings of the experiment carried out on the locust. It is observed that 5 nm sphere shape gold nanoparticles functionalized with thiol group can be transported to locust brain by the aerosol-based delivery approach. This insight finding is the evidence for axonal transport of nanoparticles to the brain that may help to deliver the drug in an effective manner. Besides nanomedicine malnutrition and food availability is a major problem for the growing about 7.8 billion world population. In this direction nanonutrient fertilizer was developed to enhance crop production by harvesting more sunlight and native nutrient mobilization in the rhizosphere. Nanonutrient improves chlorophyll and protein content in plant leaves biomass production and nutritional content in the ripened fruit. Novel nano-fertilizer not only reduces the demands of conventional chemical fertilizers and save natural resources but also improve human health by producing nutrition rich food products. In addition to nanomedicine and nanofood it is very important to detect and eradicate disease-causingagent. Thus highly sensitive graphene-based nanosensor nanopesticides and engineered water nanostructure was developed. In the mirror view of nano-biotechnology toxicity or undesirable impact of technology can’t be ignored. Therefore environmental toxicity and impact assessment based on nanoparticles morphology and composition of nanomaterials was studied. Eco-toxicity on the terrestrial and aquatic environment is investigated and factor for nanoparticles accumulation agglomeration aggregation interaction with bio-interface and fate of nanoparticles was also determined.BIOGRAPHY: Dr. Ramesh Raliya is currently a post-doctoral research scientist in the Department of Energy Environmental and Chemical Engineering at Washington University in St. Louis USA.Before this he was a research associate at Central Arid Zone Research Institute Jodhpur(An institute of Indian Council of Agriculture Research Government of India).Dr. Raliya has an interdisciplinary academic and research background. He earned his bachelor's in Bioscience and Masters in Biotechnology from Jai Narain Vyas University Jodhpur.He obtained his Ph.D. degree in 2012 from Central Arid Zone Research Institute Jodhpur India.In October 2013 he joined chemical engineering department at Washington University in St. Louis.Dr. Raliya’s research is in the area of the nanoparticle technology. With expertise in advanced functional nanomaterial synthesis using biological chemical and aerosol route he is interested in the use of nanomaterials for the advancement in health care and plant nutrition. He is also interested in addressing the long- term consequences of nanoparticles on human health.In last three years he published over 20 peer-reviewed research papers six patents(out of them one is commercialized by Govt. of India) and co-authored two books one on nanotechnology.