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Nanoparticle-encapsulated microfibers as vehicles for targeted drug delivery

Microfluidics provides a facile platform for generation of several biomaterials such as particles, capsules, microfibers, etc. The versatility of microfluidics based methods arises from the ability to control size, morphology, and composition of the generated entities. In this project the student will use microfluidic devices to generate drug and nanoparticle encapsulated microfibers for targeted drug delivery in pancreatic cancer. The encapsulated nanoparticles (iron oxide) will allow magnetic based controlled release of the drug to the targeted site.

Multiscale CFD simulations of viscoelastic turbulence

With modern-day computers and several open-source CFD packages, it is today quite straightforward to simulate Newtonian flows. Even for turbulent flows, several well-tested and efficient algorithms are available, so that reasonably high-Re Newtonian turbulence can be simulated on a personal laptop. The situation is dramatically different for Non-Newtonian flows, however, and their accurate simulation, especially in turbulent settings, remains an outstanding challenge.