Our group works on unexcitable and excitable biomemetic cells, made up of Giant Unilamellar Vesicles using experiments, theory and simulation as well. The objective in these works is to understand the complex multiphysics in these systems involving hydrodynamics, electrostatics and kinetics and membrane mechanics. In the past, we have conducted studies on electroporation and excitation of these systems. The proposed work will extend these studies for relevance to realising bio-memetic cells suitable for electroporation physics as well as extending phenomenological models to physics informed ML models. The work will involve all three components, experiments, theory and simulations.

Recent references:
Compound giant unilamellar vesicles as a bio-mimetic model for electrohydrodynamics of a nucleate cell R Kumar, R Chakrabarti, RM Thaokar Soft Matter 20 (35), 6995-7011, 2024
Electrohydrodynamics of vesicles and capsules K Priti Sinha, S Das, RB Karyappa, RM Thaokar, Langmuir 36 (18), 4863-4886, 2020