Organ-on-chip technologies are emerging as important tools for creating realistic laboratory models of human tissues, with applications in drug testing and disease studies. This project aims to design, fabricate, and experimentally validate microfluidic organ-on-chip platforms that mimic essential features of real tissues. The work will involve computer-aided design of microscale devices, soft-lithography or laser-based fabrication, basic material and surface characterization, and operation of microfluidic systems under controlled flow conditions. Students will test and validate the platform using cell-based experiments to demonstrate its ability to reproduce key functional responses. The project provides hands-on experience in microfabrication, microfluidics, and experimental validation at the interface of chemical engineering and biomedical applications. An interest in biological systems is required, but all necessary concepts and experimental techniques will be taught during the project.