Biomolecular Engineering

Topic 4: Metabolic engineering of methanotrophs for the production of liquid fuels from biogas

Guide:  Prof. Pramod Wangikar.  read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Modelling
  • Optimisation
  • Systems Biology

Topic 3: Development of synthetic biology tools for cyanobacteria.

Guide:  Prof. Pramod Wangikar.  read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Data Analysis
  • Modelling
  • Optimisation
  • Systems Biology

Topic 2: Non-stationary 13C-Metabolic flux analysis of non-model organisms.

Guide:  Prof. Pramod Wangikar.  read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Modelling
  • Systems Biology

Topic 1. Development of efficient bioprocesses for the production, purification and PEGylation of therapeutic proteins

 read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Modelling
  • Optimisation

Theoretical models to understand evolutionary processes.

In the story of evolution from a single cell (LUCA: https://en.wikipedia.org/wiki/Last_universal_common_ancestor) to complex eukaryotes, there are several missing links. In this project, we aim to develop theoretical and computational models to analyze these missing aspects in our understanding of evolution of life on Earth.  read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Computational Biology
  • Enzymology
  • Systems Biology

Modeling and simulation of endoplasmic reticulum stress pathways (TA/FA)

Endoplasmic reticulum (ER) is responsible for many important cellular functions such as
folding of proteins, glycosylation and quality control etc. Many
environmental and genetic perturbations such as hypoxia, glucose deficiency, overload of unfolded protein can lead to ER stress. ER stress has been associated with pathogenesis of many diseases
such as diabetes, neurodegenarative diseases such as Alziemers and
Parkinsons. Further, industrial recombinant mammalian cell lines producting recombinant therapeutics are also subject to ER stress.  read more »

Proposing Faculty
Research Area
  • Biochemical Engineering
  • Biomolecular Engineering
  • Computational Biology
  • Systems Biology

Genomic study of antibiotic resistance mechanisms (TA/FA)

Antibiotics have been critical for the dramatic rise of life expectancy and the fight against many diseases and infections in the past fifty years. However, over the past decade, antimicrobial resistance has emerged as a major public-health crisis. We are using Streptomyces coelicolor and Mycobacterium smegmatis as models to decipher the various mechanisms employed by bacteria to counter antibiotics. A transcriptomic study using whole-genome microarrays revealed a combination of mechanisms that Streptomyces uses to counter fluoroquinolones.  read more »

Proposing Faculty
Research Area
  • Biomolecular Engineering
  • Systems Biology
Supreet Saini
Ganesh A Viswanathan

Freeze Dryer

Freeze dry_Labconco.jpg

Freeze drying or lyophilization is the process of drying a material that has been frozen, without going through the liquid phase. The FreeZone 2.5 Liter Benchtop Freeze Dry Systems have dual refrigeration systems for small load of samples with very low eutectic points. The dehydration technique enables liquid or slurry products which have previously been frozen to be dried under a vacuum.
Web Links:
http://www.labconco.com/_scripts/editc25.asp?catid=347
http://www.directindustry.com/prod/labconco/laboratory-freeze-dryer-3070...

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