Seminars

Bibliomics plays an important role in Systems Biology along with the other “omics” such as genomics proteomics metabolomics etc. During last decade the data published in biomedical literature has grown exponentially. Many text mining algorithms and approaches have been developed to extract information from the existing literature. One such important information that exists in the literature is the associations between biological entities like the genes proteins drugs diseases etc.

ABSTRACT: Understanding and controlling interactions between colloids surfactants polymers and their mixtures is important to design new materials and to tailor many emulations that are used in day-to-day life. In this talk effect of particle shape on structure thermodynamics and surface rheology of two dimensional (2D) suspensions will be discussed. We explore the effect of particle aspect ratio and surface chemistry on particle stabilized ‘Pickering’ emulsions. The results shed some light on the role of surface rheology of the particle film in emulsion stabilization.

Note: This is a seminar in the Research Exposure seminar series and is mandatory for all 1st year M Tech and PhD students. There will be few more seminars of this type covering different research area and will be delivered by the department faculty. Attendance will be taken. Regards Pramod.

Abstract: In many biopharmaceutical filtration applications filter sizing safety factors of 1.5 are commonly used. This may lead to oversizing or undersizing of a process unit operation depending on the application and drug product. In this presentation we provide a rationale for assigning safety factor values based on designing a robust process that allows for scale differences process variability data extrapolation and process expansion.Analysis of a filtration cost model that includes process variability leads to a safety factor definition. Safety factors can vary from 1.2 to 2.5.

Abstract:A panoramic view is provided of the metabolic modeling landscape covering various approaches in the literature within a logical framework and evaluating their potential for rational analysis of significant aspects of metabolic processes and metabolic engineering. Static and dynamic (cybernetic) approaches are evaluated within the framework of metabolic network analysis in terms of elementary modes elucidating their mutual relationships and predictive capabilities.

Abstract: Emerging applications in biochemical analysis increasingly require large number of experiments performed in smaller amount of time. Moreover in most instances these ever-increasing number of experiments need to be performed using a limiting amount of starting biological sample. This requires scaling down of the analysis methods and analogous to the integrated microelectronic-chip revolution microfluidic chips are starting to transform the field of biochemical analysis.

Abstract: Drops and bubbles in confined domains are encountered in a variety of applications such as oil recovery solvent extraction and paper-making. In this talk I will present our experimental as well as numerical results for the steady shape and mobility of viscous drops and bubbles rising in cylindrical and square channels. The effects of Bond number Weber number and the presence of surfactants on the steady shapes and terminal velocities of the drops and bubbles are explored. As the Bond number increases drops become more deformed.

Abstract: On-line monitoring of particle shape and size distribution is a challenge frequently faced by the traditional pharmaceuticals and fine chemicals industries. The control of particulate processes is particularly compounded by the lack of process understanding and in-situ sensors.

Abstract : Two algorithms for simulating multiphase flow will be discussed. Due to the complexity of multiphase flow and due to the existence of multiple scales it is a formidable task to develop a generic computational algorithm applicable for all the flow configurations. However multiphase flow can loosely be categorized as i) well dispersed flow and ii) flow with distinct interface. The algorithms are developed for these two typical hydrodynamic situations. Bubbly flow has been taken as the example of well dispersed or mixed flow.

Abstract: Thermo-sensitive hydrogels are a class of stimuli-sensitive hydrogels which can undergo a significant volume transition in response to change in the temperature of the surrounding environment. Most thermo-sensitive hydrogels exhibit a characteristic temperature called Lower Critical Solution Temperature (LCST) at which they experience the volume transition. In this work we have studied a thermo-sensitive hydrogel poly(N-isopropylacrylamide) (PNIPAM) that shows an LCST at 32C.