Simulation and fabrication of occlusion devices for heart surgery
You will develop customized grafts for closing holes in hearts, by using 3D printing and other fabrication technologies. You will develop new designs, simulate them, and of fabricate a few. For these bio-resorbable scaffolds you will develop computer simulation models for degradation and mechanical behavior. You will test the structures you make by physico-chemical and biological means: in a lab setup, in-vitro in mammalian cell culture, and in-vivo in small animals, and plan for future tests in humans. The 3D printed occlusion (blocking) devices we develop will be used to close holes in the heart that are congenital defects some babies are born with.