Introduction to biosystems: microorganisms, molecules, genetics, recombinant DNA systems. Principles of enzyme catalysis: enzyme kinetics, enzyme inhibition, enzyme and cell immobilization. Microbial growth and production: stoichiometry, energetics, unstructured and structured models, flux analyses, control analysis. Bioreactors: CSTR, PFR, fed batch, gas-liquid mass transfer, power requirements, control, data acquisition, sterilization, high-cell density cultivation. Separation methods: centrifugation, filtration, ultrafiltration, precipitation, chromatography, and electrophoresis. read more »
Biochemical EngineeringGenetic engineering for production of aromatic products
Statistical design of experiments for fermentatin optimization
Topic 2:Theromdynamics of the liquid state
Topic 1:Ammonia & Nitrate removal from water
Quantification and Analysis of metabolism
Adaptive Control of Bioreactors
Scope and possibilities, characteristics and classification of biological matter, kinetics of microbial growth, balance equations for batch and continuous cultures, kinetics of enzyme catalysed reactions. Analysis of mixed microbial populations. Design and anlaysis of biological reactors. Production Isolation and utilization of enzymes. Transport phenomena in biological systems.
Offerings for this Course
Structured growth models; compartmental models, cybernetic and optimal models, stoichiometric models, immobilized enzyme kinetics, multi-enzyme kinetics. Reactor design, use of structured models, bubble column reactors, fed-batch operation, immobilized cell reactors, immobilized cell reactor/separator, simultaneous enzyme and cell reactors. Metabolic Engineering, Flux analysis, Biochemical Systems Theory (BST), Metabolic Control Analysis (MCA), Genetic models, Protein production kinetics, Analysis of genetic switches.