GC-MS is a powerful analytical technique for separation, identification and quantification of volatile organic and inorganic compounds in a solvent mixture. It is an elegant interfaced instrument, in which the Gas chromatography (GC) first separates the components of a mixture and then the coupled Mass spectrometer (MS) characterizes each of the separated components individually. The components are separated based on their relative affinity or retention time of the individual compounds. During the process, the well separated compounds from the GC are transferred to the interfaced MS instrument and get fragmentized into ions by ionization process. The resulted fragmented ions gets separated based on their m/z (Mass/Charge) ratio and it generates a mass spectrum (Distribution of mass to charge ratio Vs Signal intensity) for each component. This instrument is extensively used in the Medical, Pharmacological and Law enforcement fields.
Gas Chromatography Mass Spectrometer DSQ II